Day 1 - 2: Take one capsule one hour before a meal
Day 3 - 4: Take one capsule twice daily, one hour before meals
Day 5+: Take two capsules twice daily, one hour before meals
Max: Four capsules daily. Best results when taken on an empty stomach
![How to take Calocurb](http://wholesale.calocurb.com/cdn/shop/files/dosing-schedule.png?v=1715145292&width=500)
Our 125mg capsules allow people to customise their dosage to best fit their body’s needs and gastric emptying rate.
Up to 4 capsules can be taken to reach the recommended dose (GRAS approved 500 mg for hops). Best results observed when taken on an empty stomach. We recommend that your patients continue using Calocurb for at least one month to allow sufficient time for its appetite control benefits to fully develop.
Taking Calocurb for the first time may cause a mild stomach irritation and a laxative effect which should cease after 24-48 hours of use. This effect is based on the presence and activity of the cells responding to the Amarasate stimulation which is why it is advised to build up the dosage over three days.